【2025-09-12】 Spin states matter – fundamentals, applications and translation to drug discovery
发布时间:2025年08月27日

Prof. Dr. Rene M. Koenigs

University of Bayreuth

报告时间:9月12日15:30-17:00

报告地点: 张江校区6号楼2楼宣讲厅

邀请人: 吴晶晶 副教授


报告摘要(Abstract):

Carbenes and nitrenes are versatile reactive intermediates that find widespread application in organic synthesis. Their high reactivity, however, often necessitates the use of metal complexes for stabilization of such species.
Herein, we describe our recent approaches towards photochemical and photocatalytic carbene and nitrene transfer reactions. Strategies in accessing either singlet or triplet carbenes will be discussed and their applications in synthesis methodology will be presented. We conclude with a discussion of a collaborative approach towards drug discovery, where fundamental discoveries can be translated into new drugs and medicines.

报告人简介(Brief introduction):

Rene studied chemistry at Goethe University Frankfurt am Main from 2002 to 2008. In 2011, he obtained his PhD degree at RWTH Aachen University under the supervision of Prof. Dr. Magnus Rueping. Since Oct. 2015, he moved to RWTH Aachen University as assistant professor, and was promoted to full professor in May 2022. Since April 2025, he takes chair of Organic Chemistry at University of Bayreuth. His research focuses on organic synthesis, photochemistry, carbene/nitrene chemistry etc. He has published over 100 papers in top journals such as Science, Nat. Commun., Angew. Chem. Int. Ed., etc. Also, he has received numerous awards, including the Thieme Journal Award, RWTH Aachen FAMOS award for excellence in leadership, Future Fellowship of the Australian Research Council, Anhui Province Foreign Expert Talent Program (安徽省外专百人计划项目).