讲座报告
【2024-10-15】 New Reactions, Catalysts, and Natural Products: Inspiration and Invention in Organic Synthesis
发布时间:2024年10月12日

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Simon Blakey 教授

Emory University

报告时间:10月15日(星期二)16:00-17:30

报告地点:张江校区6号楼 二楼宣讲厅

邀请人:马佳佳 副教授



个人简介

Simon received his B.Sc. degree at the University of Auckland in 1997 and completed his Ph.D. in 2002 under the direction of Prof. Ian Paterson at the University of Cambridge. After three years as a postdoctoral fellow with Prof. David MacMillan at the California Institute of Technology, Simon joined the faculty at Emory University in the fall of 2005. Today his research interests revolve around the development of new organometallic catalysts and synthetic methodology, and the implementation of these technologies to impact both drug discovery and materials science.

报告摘要

The development of new reactions and catalysts for the oxidative cross-coupling of C-H bonds with C-H, N-H and O-H bonds will be discussed. Strategically, these reactions allow for the synthesis of complex molecules from their constituent components, minimizing the need for functional group activation and manipulation. A novel planar chiral catalyst platform for enantioselective reactions will be presented. Illustrative examples of emergent applications will be provided, and a new traceless directing group concept for C-H annulation to form heterocycles will be presented.