报告人：Prof. Hideki Yorimitsu

报告人单位：Kyoto University

报告时间：2024年9月19日 15:30-17:00

报告地点：张江校区6号楼二楼宣讲厅

邀请人：朱晨 长聘教授

报告摘要

The reductive metalation of π bonds is a well-known reaction that typically leads to the formation of protonated products such as trans-alkenes and 1,4-cyclohexadienes via carbanions. However, the use of such reactions for non-protonative transformations has been limited due to the instability of radical anion or dianion intermediates. In this talk, he will discuss recent developments in the generation of carbanions by reductive metalation of unsaturated compounds in the presence of reduction-resistant electrophiles, aiming at adding values to simple unsaturated molecules by increasing molecular complexity. Specifically, he will focus on the use of trialkoxyboranes as reduction-resistant electrophiles that can trap carbanions via their vacant p orbitals.

报告人简介

Prof. Hideki Yorimitsu has been a professor at Kyoto University since 2015. His research spans organic synthesis, organometallic chemistry, carbanion chemistry, transition metal catalysts, synthetic radical chemistry, organosulfur chemistry, and aromatic metamorphosis. He holds key editorial and leadership roles, including Associate Editor of SYNTHESIS and Vice-Dean of Kyoto University's Graduate School of Science. He has received numerous awards, such as the the Swiss Chemical Society Lectureship Award, Japan Academy Medal and JSPS Prize, and others. His recent reviews cover diverse topics like C–S bond activation and carbon–carbon bond cleavage at allylic positions.