Dr. Adam Noble

University of Bristol

报告时间：10月7日15：30-16：45

报告地点: 张江校区6号楼2楼宣讲厅

邀请人: 吴晶晶 副教授

报告摘要(Abstract)：

Organoboron compounds are highly valuable synthetic intermediates in organic chemistry, which also have important applications in medicinal chemistry, with boronic acids and their derivatives being found in several approved pharmaceuticals. As a result, there is a need for synthetic methodologies that can incorporate boron into organic molecules with high efficiency and excellent substrate generality. This lecture will focus on our recent contributions to photoinduced borylation reactions that enable a variety of readily available functional groups to be converted into boronic ester products. Furthermore, the synthetic utility of boronic esters as radical-stabilizing groups and precursors to alkyl radicals in a range of deboronative functionalization reactions will be discussed.

报告人简介(Brief introduction)：

Adam obtained his undergraduate Master’s degree in chemistry from the University of Nottingham in 2008. He completed his PhD with Professor Jim Anderson at University College London (2008-2012) before moving to the USA for a postdoc with Professor Dave MacMillan at Princeton University (2012-2014). He then returned to Prof. Varinder Aggarwal’s group at the University of Bristol as a Postdoc. In 2017, he was promoted to Research Officer in the Aggarwal group, where he took on a leading role in supervising the photochemistry projects within the group. In 2022, he was promoted to Research Fellow (equivalent to Assistant Professor), where he still leads the photochemistry projects within the Aggarwal group as well as directing his own independent research.