报告人： A. Stephen K. Hashmi 教授，海德堡大学
A. Stephen K. Hashmi is Professor for Organic Chemistry at the University of Heidelberg. From 2013 to 2019, he was Vice Rector for Research and Transfer.
With his pioneering work in the field of homogeneous gold catalysis, he has gained worldwide fame. His research focuses on the production of new gold catalysts and the development of innovative synthesis methods and detailed mechanistic studies. Potential applications are in the production of active ingredients for pharmaceuticals and compounds for materials science, e.g. in the field of organic electronics.
A. Stephen K. Hashmi has been awarded a Lectureship at the Czech Academy of Sciences, the Tan Kah Kee Chemistry Lectureship at Xiamen University (China) and the Fred Pattison Senior Lectureship at the University of Western Ontario (Canada). He is a member of the ChemPubSoc Europe, the German Chemical Society, the Amercian Chemical Society, honorary member of the Argentinian Society for Organic Chemistry and holds an honorary professorship at King Abdulaziz University (Saudi Arabia). Since 2016 A. Stephen K. Hashmi has also been editor of the Springer/Nature Journal "Gold Bulletin".
Triggered by new reactivity patterns discovered in 2000, gold catalysis has become a very successful sector of catalysis research. After methodology development and mechanistic studies in the last years applications in total synthesis became a hot topic in gold catalysis. Typical intermediates would be vinylgold/arylgold species or gold carbene species, recently also gold vinylidene intermediates, in the last two years even photoredox catalysis with gold complexes evolved, including catalytic cycles involving gold (I) and gold (III). Gold-catalyzed reactions involving functionalized gold carbene intermediates represent another new and significant variation of the reactivity patterns of gold catalysis. New reactivity patterns will be discussed in detail with a number of new reactions, the presentation will combine both experimental and computational results. Examples will involve the use of anthranils, 1,2,4-oxadiazoles and 1,3,5-triazinanes. Furthermore, oxygen transfer to the functionalized carbene centers and insertions into alkyl-C,H bonds will be addressed in detail.