吴龙飞
职称:长聘教轨副教授
电子邮箱:lfwu1988@gmail.com
办公地点:张衡路429号吕志和科学园4号楼
电话:021-
个人网页/课题组主页:
RNA共价自组装及结构功能涌现
功能RNA和蛋白质的体外筛选进化
基因信息复制和翻译编码的起源及拓展
2010.09-2016.01,上海有机化学研究所,博士学位,导师:唐功利研究员
2006.09-2010.07,复旦大学,药学院,学士学位
2022.12-2024 , 芝加哥大学/霍华德休斯医学研究所,博士后,合作导师:Jack Szostak 教授
2021.04-2022.12, 哈佛大学医学院/麻省总医院,博士后,合作导师:Jack Szostak 教授
2016.04-2021.04,英国医学委员会-分子生物学实验室,博士后,合作导师:John Sutherland教授
2016.03-2016.04,上海有机化学研究所,科研助理,合作导师:唐功利研究员
Wu, L.-F.; Liu, Z.; Roberts, S. J.; Su, M.; Szostak, S. W.*; Sutherland, J. D.* Template-free assembly of functional RNAs by loop-closing ligation. J. Am. Chem. Soc. 2022, 144,13920-113927.
Wu, L.-F.†; Su, M.†; Liu, Z.; Bjork, S. J.; Sutherland, J. D.* Interstrand aminoacyl transfer in a tRNA acceptor stem-overhang mimic. J. Am. Chem. Soc. 2021, 143, 11836-11842.
Naydenova, K.†; Muir, K. W.†; Wu, L.-F.†; Zhang, Z.; Coscia, F.; Peet, M. J.; Castro-Hartmann, P.; Qian, P.; Sader, K.; Dent, K.; Kimanius, D.; Sutherland, J. D.*; Löwe, J.*; Barford, D.*; Russo C. J.* Structural basis for the inhibition of the SARS-CoV-2 RNA-dependent RNA polymerase by favipiravir-RTP. Proc. Natl. Acad. Sci. U.S.A 2021, 118, e2021946118.
Wu, L.-F.*; Liu, Z.; Sutherland, J. D.* pH-Dependent peptide bond formation by the selective coupling of α-amino acids in water. Chem. Commun. 2021, 57, 73-76.
Liu, Z.†; Wu, L.-F.†; Xu, J.; Bonfio, C.; Russell, D. A.; Sutherland, J. D.* Harnessing chemical energy for the activation and joining of prebiotic building blocks. Nat. Chem. 2020, 12, 1023-1028.
Wu, L.-F.†; He, H.-Y.†; Pan, H.-X.; Han, L.; Wang, R.; Tang, G.-L.* Characterization of QmnD3/QmnD4 for double bond formation in quartromicin biosynthesis. Org. Lett. 2014, 16, 1578-1581