研究方向

• 理论与计算有机化学

• 过渡金属催化反应机制与选择性

• 酶催化反应机制与选择性

教育工作经历

教育背景：

• 2014.09-2017.06 中国科学院化学研究所，博士

• 2011.09-2014.07 首都师范大学，硕士

• 2007.09-2011.07 山东师范大学，学士

工作经历：

• 2017.12-2023.12美国加州大学洛杉矶分校，博士后

• 2017.07-2017.11中国科学院化学研究所，研究助理

荣誉与获奖

• Chancellor's Award for Postdoctoral Research (2022, UCLA)

• Wiley Computers in Chemistry Outstanding Postdoc Award (2022, ACS fall meeting)

• 北京市优秀毕业生（2017，北京市教育委员会）

• 中国科学院大学优秀毕业生 （2017， 中国科学院大学）

• 中国科学院化学研究所“所长优秀奖”（2017，中国科学院化学研究所）

• 中国科学院化学研究所青年科学奖优秀奖（2015，2016，中国科学院化学研究所）

• 博士研究生国家奖学金（2016，中华人民共和国教育部）

• 中国科学院大学三好学生（2015, 2016，中国科学院大学）

• 山东师范大学优秀学生（2009, 2010，山东师范大学）

代表性论文和论著

• Zhoulong Fan#, Xiangyang Chen#, Keita Tanaka, Han Seul Park, Nelson Y. S. Lam, Jonathan J. Wong, K. N. Houk*, Jin-Quan Yu*; Molecular Editing of Aza-arene C–H Bonds by Distance, Geometry and Chirality; Nature. 2022, 610, 87–93. (co-first author)

• Xiangyang Chen#, Mathias Kirk Thøgersen#, Limin Yang, Rune F. Lauridsen, Xiao-Song Xue, Karl Anker Jørgensen*, and K. N. Houk*; [8+2] vs [4+2] Cycloadditions of Cyclohexadienamines to Tropone and Heptafulvenes—Mechanisms and Selectivities; J. Am. Chem. Soc.2021, 143, 934-944.

• Jiahang Lv#, Xiangyang Chen#, Xiao-Song Xue, Binlin Zhao, Yong Liang, Minyan Wang, Liqun Jin, Yu Yuan, Ying Han, Yue Zhao, Yi Lu, Jing Zhao, Wei-Yin Sun, K. N. Houk*, and Zhuangzhi Shi*; Metal-free directed sp2-C–H borylation. Nature 2019, 575, 336-340. (co-first author)

• Hao Wang#, Zhongyu Li#, Xiangyang Chen#, Jonathan J. Wong#, Tongyu Bi, Xiankun Tong, Zhongliang Xu, Mingyue Zheng, Yunhui Wan, Li Tang, Bo Liu, Xinlei Zong, Jianping Zuo, Li Yang*, Wei Huang*, Kendall N. Houk* and Weibo Yang*; Multicomponent coupling and macrocyclization enabled by Rh (III)-catalyzed dual C–H activation: Macrocyclic oxime inhibitor of influenza H1N1; Chem. 2023. 9, 607-623. (co-first author)

• Zheng-Jun Wang#, Xiangyang Chen#, Lei Wu, Jonathan J. Wong, Yong Liang, Yue Zhao, K. N. Houk, * and Zhuangzhi Shi*; Metal-Free Directed C-H Borylation of Pyrroles. Angew. Chem. Int. Ed. 2021, 60, 8500-8504. (co-first author)

• Dingyi Wang#, Xiangyang Chen#, Jonathan J. Wong, Liqun Jin, Mingjie Li, Yue Zhao, K. N. Houk*, and Zhuangzhi Shi*; Phosphorus (III)-assisted regioselective C-H silylation of heteroarenes. Nat. Commun. 2021, 12, 524. (co-first author)

• Xiangyang Chen, Hongyu Ge and Xinzheng Yang*; Newly Designed Manganese and Cobalt Complexes with Pendant Amines for the Hydrogenation of CO2 to Methanol: a DFT Study; Catal. Sci. Technol. 2017, 7, 348-355. (Outside back cover)

• Xiangyang Chen and Xinzheng Yang*; Bioinspired Design and Computational Prediction of Iron Complexes with Pendant Amines for the Production of Methanol from CO2 and H2; J. Phys. Chem. Lett. 2016, 7, 1035-1041.

• Xiangyang Chen, Yuanyuan Jing and Xinzheng Yang*; Unexpected Direct Hydride Transfer Mechanism for the Hydrogenation of Ethyl Acetate to Ethanol Catalyzed by SNS Pincer Ruthenium Complexes; Chem. - Eur. J. 2016, 22, 1950-1957. (Hot paper)

• Xiangyang Chen, Yuanyuan Jing and Xinzheng Yang*; Computational Design of Iron Diphosphine Complexes with Pendant Amines for Hydrogenation of CO2 to Methanol: A Mimic of [NiFe]-Hydrogenase; Chem. - Eur. J. 2016, 22, 8897-8902.