课题组长

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唐克轩 (兼职PI)

职位:特聘教授

电子邮箱:kxtang@sjtu.edu.cn

办公地点:上海市东川路800号上海交通大学农业与生物学院大楼1区405室

电话:021-021-34206916

个人网页/课题组主页地址:

研究方向:

  • 合成生物学

  • 植物代谢调控与代谢工程

  • 生物反应器

教育背景:

  • 1991-1996       英国诺丁汉大学,生命科学系,博士

  • 1985-1988      北京农业大学,作物遗传育种专业,硕士

  • 1981-1985      四川大学,生物系 ,学士

工作经历:

  • 2003-至今     上海交通大学,教授

  • 1996-2003     复旦大学遗传工程国家重点实验室,教授

学术任职、荣誉与获奖:

       于1997、1998和1999年获得美国洛克菲勒基金会职业奖学金到英国John Innes研究中心和美国加州大学Davis分校开展植物生物技术领域合作研究。曾任上海交通大学农业与生物学院院长、国家863“十五”计划生物工程技术主题专家和生物反应器重大专项专家、5个国家重点实验室(遗传工程、植物分子遗传、作物遗传改良、热带作物生物技术、水稻生物学)和国家转基因植物及产业化基地等学术委员会委员及SCI期刊<<Molecular Plant >>编委。

       现任上海交通大学特聘教授、植物生物技术研究中心主任、复旦-交大-诺丁汉植物生物技术研发中心主任。国务院特殊津贴获得者、上海市优秀学科带头人、上海市领军人才、瑞典林奈大学名誉博士。兼任国际园艺学会观赏植物分会副主席、上海市生物工程学会副理事长,曾任中国植物生理与分子生物学会常务理事、上海市植物生理与分子生物学会副理事长、上海市第十一届、第十二届政协委员。担任SCI期刊<<Plant Cell, Tissue and Organ Culture >>和<<Biotechnology and Applied Biochemistry >>副主编、<<Frontiers in Plant Science>> 和<<BioMed Research International>> 、 <<Frontiers of Agricultural Science and Engineering >>编委,核心期刊<<农业生物技术学报>>、<<植物学报>>、<<应用与环境生物学报>>和<<中国生物工程杂志>>等编委。

代表性学术成果

  • Danial, H., Fu, X., Shen, Q., Khalid, M., Rose, J.K.C. and Tang, K. (2020). Parallel Transcriptional Regulation of Artemisinin and Flavonoid Biosynthesis. Trends in Plant Science 25(5): 466-476.

  • Ma, Y., Xu, D., Li, L., Zhang, F., Fu, X., Shen, Q., Lyu, X., Wu, Z., Pan, Q., Shi, P., Hao, X., Yan, T., Chen, M., Liu, P., He, Q., Xie, L., Zhang, Y., Tang, Y., Zhao, J., Zhang, L., Sun, X. and Tang, K. (2018). Jasmonate promotes artemisinin biosynthesis by activating the TCP14-ORA complex in Artemisia annua. Science Advances 4, eaas9357.

  • Shen, Q., Zhang, L., Liao, Z., Wang, S., Yan, T., Shi, P., Liu, M., Fu, X., Pan, Q., Wang, Y., Lv, Z., Lu, X., Zhang, F., Jiang, W., Ma, Y., Chen, M., Hao, X., Li, L., Tang, Y., Lv, G., Zhou, Y., Sun, X., Brodelius, P.E., Rose, J.K.C and Tang, K. (2018). The genome of Artemisia annua provides insight into the evolution of Asteraceae family and artemisinin biosynthesis. Molecular Plant 11: 776-788.

  • Shi, P., Fu, X., Shen, Q., Liu, M., Pan, Q., Tang, Y., Jiang, W., Lv, Z., Yan, T., Ma, Y., Chen, M., Hao, X., Liu, P., Li, L., Sun, X. and Tang, K. (2018). The role of AaMIXTA1 in regulating the initiation of glandular trichomes and cuticle biosynthesis in Artemisia annua. New Phytologist 217:261-276.

  • Yan, T., Li, L., Xie, L., Chen, M., Shen, Q., Pan, Q., Fu, X., Shi, P., Tang, Y., Huang, H., Huang, Y., Huang, Y. and Tang, K. (2018). A novel HD-ZIP IV/MIXTA complex promotes glandular trichome initiation and cuticle development in Artemisia annua. New Phytologist 218: 567–578.

  • Yan, T., Chen, M., Shen, Q., Li, L., Fu, X., Pan, Q., Tang, Y., Shi, P., Lv, Z., Jiang, W., Ma, Y., Hao, X., Sun, X. and Tang, K. (2017). HOMEODOMAIN PROTEIN 1 is required for jasmonate-mediated glandular trichome initiation in Artemisia annua. New Phytologist 213(3): 1145-1155.

  • Chen, M., Yan, T., Shen, Q., Lu, X., Pan, Q., Huang, Y., Tang, Y., Fu, X., Liu, M., Jiang, W., Lv, Z., Shi, P., Ma, Y., Hao, X., Zhang, L., Li, L. and Tang, K. (2017). GLANDULAR TRICHOME-SPECIFIC WRKY 1 promotes artemisinin biosynthesis in Artemisia annua. New Phytologist 214(1): 304-316.

  • Tang, K., Shen, Q., Lu X. and Zhang, F. (2016). Improving artemisinin content in Artemisia annua by transcription factor regulation. Science (supplement): 48-51.

  • Shen, Q., Yan, T., Fu, X. and Tang, K. (2016). Transcriptional regulation of artemisinin biosynthesis in Artemisia annua L. Science Bulletin 61(1): 18-25.

  • Shen, Q., Lu, X., Yan, T., Fu, X., Lv, Z., Zhang, F., Pan, Q., Wang, G., Sun, X. and Tang, K. (2016). The jasmonate-responsive AaMYC2 transcription factor positively regulates artemisinin biosynthesis in Artemisia annua. New Phytologist 210: 1269-1281.

  • Zhang, F., Fu, X., Lv, Z., Lu, X., Shen, Q., Zhang, L., Zhu, M., Wang, G., Sun, X., Liao, Z. and Tang K. (2015). A basic leucine zipper transcription factor, AabZIP1, connects abscisic acid signaling with artemisinin biosynthesis in Artemisia annua. Molecular Plant 8: 163-175.

  • Lv, Z., Zhang, F., Pan, Q., Fu, X., Jiang, W., Shen, Q., Yan, T., Shi, P., Lu, X., Sun, X. and Tang, K. (2016). Branch Pathway Blocking in Artemisia annua is a Useful Method for Obtaining High Yield Artemisinin. Plant and Cell Physiology 57(3): 588-602.

  • Lu, X., Zhang, L., Zhang, F., Jiang, W., Shen, Q., Zhang, L., Lv, Z., Wang, G. and Tang, K. (2013). AaORA, a trichome-specific AP2/ERF transcription factor of Artemisia annua, is a positive regulator in the artemisinin biosynthetic pathway and in disease resistance to Botrytis cinerea. New Phytologist 198: 1191-1202.

  • Zhang, F., Zuo, K., Zhang, J., Liu, X., Zhang, L., Sun, X. and Tang, K. (2010). An L1 box binding protein, GbML1, interacts with GbMYB25 to control cotton fibre development. Journal of Experimental Botany 61(13):3599–3613.

  • Liu, X., Zuo, K., Xu, J., Li, Y., Zhang, F., Yao, H., Wang, Y., Chen, Y., Qiu, C., Sun, X. and Tang, K. (2010). Functional analysis of GbAGL1, a D-lineage gene from cotton (Gossypium barbadense). Journal of Experimental Botany 61(4): 1193-1203

  • Zhang, L., Li, Y., Wang, Z., Xia, Y., Chen, W. and Tang, K. (2007). Recent Developments and Future Prospects of Vitreoscilla Hemoglobin Application in Metabolic Engineering. Biotechnology Advances 25: 123-136.

  • Zhang, L., Wang, Z., Xia, Y., Kai, G., Chen, W. and Tang, K. (2007). Metabolic Engineering of Plant L-ascorbic Acid Biosynthesis: Recent Trends and Applications. Critical Reviews in Biotechnology 27(3):173-182.

  • Zhang, L., Ding, R., Chai, Y., Bonfill, M., Moyano, E., Oksman-Caldentey, K-M., Xu, T., Pi, Y., Wang, Z., Zhang, H., Kai, G., Liao, Z., Sun, X., and Tang, K. (2004). Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures. Proceedings of the National Academy of Sciences USA 101(17): 6786-6791.

  • Zhang, L., Yuan, D., Yu, S., Li, Z., Cao, Y., Miao, Z., Qian, H. and Tang, K. (2004). Preference of simple sequence repeats in coding and non-coding regions of Arabidopsis thaliana. Bioinformatics 20(7): 1081-1086.

  • Yao, J., Zhao, X., Liao, Z., Lin, J., Chen, Z., Chen, F., Song, J., Sun, X. and Tang, K. (2003). Cloning and molecular characterization of a novel lectin gene from Pinellia ternata. Cell Research 13(4): 301-308.

论著

  • 《植物生物技术》(张献龙、唐克轩主编,科学出版社,2004)

  • 《中草药生物技术》(唐克轩主编,复旦大学出版社,2005)

  • 《细胞工程》(陈志南主编、唐克轩副主编,科学出版社,2005)

成果专利

  • 申请或授权国内外发明专利200余项,其中授权发明专利近百项。以第一完成人获得2009年高等教育上海市级教学成果二等奖和2014年上海市技术发明二等奖。