课题组长

吴晶晶

职位:长聘教轨副教授

电子邮箱:wujingjingsjtu@sjtu.edu.cn

办公地点:上海市东川路800号,上海交通大学霞光楼

个人网页/课题组主页地址:https://www.x-mol.com/groups/sjtujingjingwu

研究方向:

  • 可见光诱导的自由基反应研究

  • 自由基反应在复杂天然产物、药物分子后期修饰中的应用

  • 具有重要生理活性的复杂甾体、三萜类天然产物的合成

教育背景:

  • 2009.09-2014.07  中国科学院上海有机化学研究所,中国科学院天然产物有机合成化学重点实验室,理学博士, 导师:田伟生 研究员

  • 2005.09-2009.06  华东理工大学,药学院制药工程系制药工程(药学)专业,工学学士, 导师:曾步兵 教授

工作经历:

  • 2021.01至今   上海交通大学变革性分子前沿学科中心,长聘教轨副教授

  • 2015.10-2020.12  英国布里斯托大学,化学系,博士后, 合作导师:英国皇家科学院院士Varinder. K. Aggarwal 教授

  • 2014.08-2015.09   中国科学院上海有机化学研究所,中国科学院天然产物有机合成化学重点实验室,助理研究员

学术任职、荣誉与获奖:

  • 曾应邀担任ACIE, Org.Lett, CCS Chemistry, Sci Bull 等期刊的审稿人。

  • 曾获得中国科学院三好学生、Merck 合成挑战赛团体冠军等荣誉。

学术成果:

  • Jingjing Wu, Robin Bär, Lin Guo, Adam Noble and Varinder K. Aggarwal., Photoinduced Deoxygenative Borylations of Aliphatic Alcohols. Angew. Chem. Int. Ed. 2019, 58, 18830 –18834. (IF:12.959)

  • Jingjing Wu, Phillip S. Grant, Xiabing Li, Adam Noble and Varinder K. Aggarwal., Catalyst-Free Deaminative Functionalizations of Primary Amines via Photoinduced Single-Electron Transfer. Angew. Chem. Int. Ed. 2019, 58, 5697-5701. (IF:12.959,SCI高被引论文)

  • Jingjing Wu, Lin He, Adam Noble and Varinder K. Aggarwal., Photoinduced Deaminative Borylation of Alkylamines. J. Am. Chem. Soc. 2018, 140, 10700−10704. (IF:14.612,SCI高被引论文)

  • Jiachen Deng†, Jingjing Wu†, Hailong Tian, Jiajing Bao, Yong Shi, Weisheng Tian* and Jinghan Gui*., Alkynes from furans: A general fragmentation method applied to the Synthesis of the Proposed Structure of Aglatomin B. Angew. Chem. Int. Ed. 2018, 57, 3617 –3621. (†equal contribution). (IF:12.959)

  • JingJing Wu, Paula Lorenzo, Siying Zhong, Muhammad Ali, Craig P. Butts, Eddie L. Myers, Varinder K. Aggarwal., Synergy of synthesis, computation and NMR reveals correct Baulamycin structures. Nature, 2017, 547, 436-440. (IF:42.778)

  • Jingjing Wu, Yong Shi*, Weisheng Tian*., Synthesis of the aglycon of Aspafiliosides E and F via a spiroketal-forming cascade. Tetrahedron. Lett., 2017, 58, 923-925. (IF:2.275,)

  • Jingjing Wu, Yong Shi*, Weisheng Tian*., Synthesis of the aglycon of Aspafiliosides E and F based on cascade reactions. Chem. Commun., 2016, 52, 1942-1944. (IF:5.996)

  • Jingjing Wu, Ran Gao, Yong Shi*, Weisheng Tian*., Direct amination of EF spiroketal in steroidal sapogenins: an efficient synthetic strategy and method for related alkaloids. Tetrahedron. Lett. 2015, 56, 6639–6642. (IF:2.275)

  • Jingjing Wu, Yong Shi*, Weisheng Tian*., Facile synthesis of solasodine based on a mild halogenation ring opening reaction of spiroketals in steroidal spogenins. Tetrahedron. Lett. 2015, 56, 1215–1217. (IF:2.275)

  • LingLi Hou, Yong Shi, ZhiDan Zhang, JingJing Wu, QingXiong Yang, WeiSheng Tian., Divergent Synthesis of Solanidine and 22-epi-Solanidine. J. Org. Chem. 2017, 82, 7463−7469. (IF:4.335)

  • ZhiDan Zhang, Yong Shi*, JingJing Wu, JingRong Lin, and WeiSheng Tian*., Synthesis of Demissidine and Solanidine. Org. Lett. 2016, 18, 3038−3040. (IF:6.091)

  • Xiang Hao, Jingjing Wu, Hailong Tian, Yong Shi*, Jingrong Lin, and Weisheng Tian*., A Short Synthesis of Clionamine D. Chin. J. Chem. 2015, 33, 1235-1238. (IF:3.826, 封面文章)

  • Wangjun *, Jingjing Wu, Weisheng Tian*., BF3•Et2O Promoted Sulfuration of Steroidal Sapogenins. Chin. J. Chem. 2015, 33, 632-636. (IF:3.826, 封面文章)

  • Xiaofei Zhang, Jingjing Wu, Yong Shi*, Weisheng Tian*., Formal synthesis of osladin based on an activation relay process. Tetrahedron. Lett. 2014, 55 ,4639–4642. (IF:2.275)

    此外申请并获授权中国专利6项(CN102153611A,CN102329368A,CN102286052A,CN103265600A,CN104530179A,CN107814717A)